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Classifying Animals by Appearance Versus DNA Sequence
Conditional Remix & Share Permitted
CC BY-NC-SA
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The topic of this video module is how to classify animals based on how closely related they are. The main learning objective is that students will learn how to make phylogenetic trees based on both physical characteristics and on DNA sequence. Students will also learn why the objective and quantitative nature of DNA sequencing is preferable when it come to classifying animals based on how closely related they are. Knowledge prerequisites to this lesson include that students have some understanding of what DNA is and that they have a familiarity with the base-pairing rules and with writing a DNA sequence.

Material Type:
Lecture
Provider:
MIT
Provider Set:
MIT Blossoms
Author:
Megan E. Rokop
Date Added:
06/11/2012
Gene Machine: The Lac Operon (AR)
Unrestricted Use
CC BY
Rating

Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.

Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
George Speigelman
Jared Taylor
John Blanco
Kathy Perkins
Noah Podolefsky
Date Added:
05/01/2010
Molecular Motors (AR)
Unrestricted Use
CC BY
Rating

Discover what controls how fast tiny molecular motors in our body pull through a single strand of DNA. How hard can the motor pull in a tug of war with the optical tweezers? Discover what helps it pull harder. Do all molecular motors behave the same?

Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
Chris Malley
Kathy Perkins
Meredith Betterton
Michael Dubson
Thomas Perkins
Wendy Adams
Date Added:
12/01/2007
Optical Tweezers and Applications (AR)
Unrestricted Use
CC BY
Rating

Did you ever imagine that you can use light to move a microscopic plastic bead? Explore the forces on the bead or slow time to see the interaction with the laser's electric field. Use the optical tweezers to manipulate a single strand of DNA and explore the physics of tiny molecular motors. Can you get the DNA completely straight or stop the molecular motor?

Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
Archie Paulson
Chris Malley
Kathy Perkins
Michael Dubson
Thomas Perkins
Wendy Adams
Date Added:
08/01/2007
Phylogenetics
Only Sharing Permitted
CC BY-NC-ND
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This activity lets learners participate in the process of reconstructing a phylogenetic tree and introduces them to several core bioinformatics concepts, particularly in relation to evolution. Groups of learners (at least 10) repeat a secret message (five to seven similar-sounding words) like the game "Telephone". In this version of the game, however, learners write and then code what they hear, creating a model of a phylogenetic tree and using a species distance matrix. This resource includes background information about phylogenetic trees, maximum parsimony, and matrix theory (see page 6-7 of PDF).

نوع المادة:
Activity/Lab
Game
Lesson Plan
Provider:
Computer Science Unplugged
Science and Math Informal Learning Educators (SMILE)
Provider Set:
Computer Science Unplugged
SMILE Pathway: Science and Math Activities in One Search
المؤلف:
Brian Mason Scientific and Technical Trust
Computer Science Unplugged
Google Inc.
Jim Becker
Katrin Becker
Truman State University
Date Added:
01/02/2005
Stretching DNA (AR)
Unrestricted Use
CC BY
Rating

Explore stretching just a single strand of DNA using optical tweezers or fluid flow. Experiment with the forces involved and measure the relationship between the stretched DNA length and the force required to keep it stretched. Is DNA more like a rope or like a spring?

Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
Chris Malley
Kathy Perkins
Meredith Betterton
Michael Dubson
Thomas Perkins
Wendy Adams
Date Added:
12/01/2007